7 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... structure and cell ... #table #differential ... #diagnosis #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... with qualitative defects ... #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... lymphoproliferative disorders ... • Neutropenia, anemia ... , thrombocytopenia ... #workup #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... with or without platelet ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... - Low Hb and platelets ... Immunohistochemical studies (to differentiate ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Marrow Failure • Chronic ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology