336 results
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Cell (RBC) Morphologies ... and Associated Diseases ... cell, Other RBC ... Howell-Jolly bodies #RBC ... #Hematology #Diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Decreased RBC ... Anemia of Chronic Disease ... Thalassemia • RBC ... Disorder • RBC ... #Algorithm #Causes
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... Bite Cell RBC: G6PD ... Target Cell RBC ... #differential #diagnosis
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... == Decreased RBC ... Glucose Content • RBC ... Reduction == Increase RBC ... Dilutional Effect • RBC
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... - Differential Diagnosis ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... #Algorithm #Causes
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
and Differential Diagnosis ... dysmorphic RBC’s, RBC ... /WBC casts, proteinuria ... intrinsic renal disease ... neck, prostatic) #Diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... 2) External (RBC ... , Drugs, Liver Disease ... 3) Internal (RBC ... #Differential #Diagnosis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria: 3 or more RBC ... hematuria: - RBC ... castsDiagnostic ... - Dysmorphic RBC ... of glomerular disease
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
glomerular hematuria (RBC ... casts or dysmorphic ... RBCs in urine)? ... Algorithm #Nephrology #Diagnosis
Interpreting Right Heart Catheterizations

Always interpret a RHC based on the indication for getting the test. This
Always interpret a RHC ... for suspicion of pulmonary ... Catheterization #RHC ... #diagnosis #pulmonary ... #hypertension #cardiology