9 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... Hematology #Clinical #Smear
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytic leukemia (APL ... and started on all-trans ... In addition to APL ... #Clinical #Path ... Rods #AuerRods #APL
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... Mature B-cell ALL ... involvement • T-cell ALL ... Pruritis after hot bath ... • Peripheral smear
Auer Rods - Bone marrow aspiration revealed 5% blasts and 65% promyelocytes; many promyelocytes had prominent
#Clinical #Path ... #APL #AuerRods # ... AcutePromyelocyticLeukemia #Smear ... #Microscopy #NEJM
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
myelogenous leukemia (AML ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Microscopy ... Rods #AuerRods #AML
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-prolymphocytic leukemia (T-PLL ... Myeloid Leukemia (AML ... Prolymphocytes #Smear ... #Peripheral #Pathology ... Microscopy #Clinical #Blood
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
disease with limited BM ... iAMP21 - BCR-ABL-like ... lauraebrown #BCell #ALL ... Leukemia #Lymphoma #hemepath ... #pathology #prognosis
Guide to systemic mastocytosis

Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
aggregates) in BM ... Minor: • >25% of all ... are atypical on BM ... #mastocytosis #hemepath ... #pathology #algorithm
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV ... not required in all ... When do you do a BM ... dysplasia on the smear