16 results
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
Diagnosis Workup Algorithm ... Primary Adrenal ... • Autoimmune primary ... apoplexy • Isolated ACTH-deficiency ... #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... High baseline ACTH ... - Primary adrenal ... Differential #Diagnosis #Algorithm ... #endocrinology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Adrenal Insufficiency ... - Pathophysiology ... be low, while ACTH ... Low ACTH leads to ... #endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Diagnosis Algorithm ... AI #Adrenal #Insufficiency ... #Diagnosis #Algorithm ... #Test #Endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal Insufficiency ... Differential Diagnosis Algorithm ... ACTH-Dependent ... (Primary): • Autoimmune ... #Causes #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal Insufficiency ... - Algorithm ... Differentiate primary ... #Algorithm #Diagnosis ... #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Diagnosis Algorithm ... skin (due to high ACTH ... , only seen in PRIMARY ... findings (see algorithm ... Stimulation #StimTest #Endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Primary Adrenal ... Insufficiency: ... autoimmune-mediated primary ... adrenal insufficiency ... diagnosis #testing #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... Diagnosis Algorithm ... pregnancy) Test 2: ACTH ... #Diagnosis #Algorithm ... #endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Insufficiency Addison's ... Causes of Adrenal Insufficiency ... ovarian insufficiency ... #adrenal #insufficiency ... addisons #disease #endocrinology