9 results
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... • Rheumatoid Arthritis ... Obstructive Pulmonary Disease ... #causes
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis Algorithm ... Granulomatous Disease ... Tumors: Lung, SCC, renal ... Bony Mets - Calcium ... #causes #endocrinology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Differential Diagnosis Algorithm ... - Hemolytic Anemia ... • Alcohol #gout ... #endocrinology ... #causes
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... synovial fluid • Gout ... urate crystals (gout ... ) or calcium pyrophosphate ... the presence of anemia
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Hypercalcemia (due to diseases ... Accumulation of calcium ... in renal tubules ... Hyperuricemia #Pathophysiology ... Complications #Gout
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... result in severe anemia ... Negative, ruling out ... the presence of renal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Malnutrition • Wilson's disease ... • Pernicious anemia ... collection with EDTA Pathophysiology ... ALP -> PPi and Calcium ... Phosphatase: • Other causes
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... our patient's out ... phlebotomy/ blood work ... of renal disease ... #pathophysiology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... • Heavy chain disease ... (RA, Temporal arteritis ... cancers, HCC, renal ... Thalassemia, Sickle cell anemia