13 results
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
Hyperpigmentation Differentials ... the Mnemonic "no skin ... #symptoms #signs ... #dermatology #skin ... #skinrash
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
red-flags to exclude dermatologic ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Diagnosis #Dermatology ... Targetoid #Algorithm #Differential
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm

Face
 • Melasma
Abdomen
 • Linea Nigra 
Hormone induced
Physiologic Skin ... in Pregnancy - Differential ... • Chadwick's sign ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin ... Auspitz sign, Koebner's ... Papulosquamous #SkinRash ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... organ-specific signs ... symptoms (eg, skin ... Disorders #Algorithm #Differential ... #diagnosis #hematology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... cold & mottled skin ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... blisters on the skin ... Collapse: • Pathophysiology ... → Syncope • Signs ... #diagnosis #causes
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Thickening of skin ... hyperthyroidism #causes ... #diagnosis #differential ... #endocrinology ... #signs #symptoms
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... Examination: • Skin ... bile ducts Differential
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... symptoms are not caused ... nodes: 13-15%, skin ... anterior/posterior MSK ... Diagnosis #Management #Signs