15 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
chromosome 21) Signs ... / Symptoms / Complications ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... / Symptoms / Complications ... of normal leg reflexes ... Syndrome #MSK #pathophysiology ... #signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... numbness, decreased reflexes ... Pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
adenomas that require treatment ... Signs / Symptoms ... / Complications ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... diffuse light reflex ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms #complications
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Perforation) Pathophysiology ... often ordered in reflex ... CT A/P: Assess complications ... KUB ↓↓Sens for complications ... • Flex-Sig: If
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... diagnosis column Treatment ... neurology #diagnosis #management