52 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... Lymphohistiocytosis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... signs and symptoms ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
: Pathogenesis and ... clinical findings ... StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Recommended Follow-up of Treated Syphilis Cases

EVIDENCE OF TREATMENT FAILURE OR POSSIBLE REINFECTION
• Persistence or recurrence of
recurrence of signs ... and symptoms • ... and symptoms • ... #Management #Guidelines ... #CDC
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Management Summary ... incidentally via CBC ... When present, symptoms ... , signs, and complications ... PV #Diagnosis #Management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... decreased reflexes Pathophysiology ... intervention CMC
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
: Pathogenesis and ... clinical findings ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
clinical findings ... pre-determined etiology Signs ... /Symptoms/Complications ... #symptoms #pathophysiology ... #msk #orthopedics
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary ... Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... not feasible CMC
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Management - GrepMed ... Handbook Clinical ... Perforation) Pathophysiology ... • Flex-Sig: If ... Treatment Guideline