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management differential hemophagocytic hlh hyperthyroidism lymphohistiocytosis signs sjogrens summary symptoms syndrome treatment
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperthyroidism Overview Clinical ... hyperthyroidism Diagnosis ... ↑ T3 - Mild hypercalcemia ... hyperthyroidism #causes ... #endocrinology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... treatment #summary #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... /aggregate) of CD4 ... salivary ducts Clinical ... and peripheral Thyroid ... Sjogrens #Syndrome #Rheumatology
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