24 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... maintained fever CAUSES ... hyperthermia crisis (late sign ... #Hyperthermia #Differential
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
carotid sinus syndrome ... syncope (ruling out differential ... orthostatic vital sign ... should be guided by clinical ... The treatment strategy
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... #oncology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
changes and may cause ... severe clinical ... hyperparathyroidism Treatment ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... Clinical DX: - ... test - Cogan sign ... - Peek sign
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Causes: - Idiopathic ... - CBC may also ... Treatment: - Systemic ... #dermatology #oncology