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diagnosis ana antibody erythematosus lupus nuclear patterns sle testing autoantibodies clues cytoplasmic differentiation management mimickers oncology signs symptoms syndrome system
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... initiation • Differential ... Differentiation #Syndrome #APML ... diagnosis #management #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... - Anti-B2GP1 (aPL ... ) 30-45% Differential ... symptoms #mimickers #differential ... #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... conditions - Sp-100, PML ... ARUPLabs #ANA #Antinuclear ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... 6) An annular rash ... search ANA and aPL ... erythematosus #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... conditions • Sp-100, PML ... ARUPLabs #ANA #Antinuclear ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
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