20 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... weakness, less systemic ... Can also see mechanics ... after 2 years of treatment ... #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... acro-osteolysis, myositis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Glomerulonephritis Myositis ... Thrombocytopenia #Lupus #SLE ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... (SLE) - Typical ... Signs/Symptoms ... Arthralgia / arthritis, Myositis ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... Sjögren Syndrome, Myositis ... Disorders, Infection, Autoimmune ... Thyroid, Autoimmune ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... life-threatening • Treatment ... #lupus #Systemic ... Management #Summary #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... #Systemic #Lupus ... autoantibodies #signs ... #differential #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... Disease, PRES Pathophysiology ... Erythematosus #SLE ... CNS #neurology #rheumatology
Anterior Non-necrotizing Scleritis - Slit Lamp Ocular Examination

This 57 yo WM reported to clinic complaining of
autoimmune conditions ... patient was sent to rheumatology ... for further systemic ... workup and treatment ... #physicalexam #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... months to years) Systemic ... • Immunologic Workup ... life-threatening • Treatment ... comparison #table #rheumatology