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diagnosis management differential hemophagocytic hlh lymphohistiocytosis syndrome workup abnormal aflp algorithm alkaline alkphos alp anorexianervosa astalt biliary bilirubin causes chemistry
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
and Bilirubin Metabolism ... insult Bilirubin metabolism ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... postpartum): • Initial symptoms ... #Pregnancy #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... The presence of metabolic ... #LFTs #Abnormal ... #Algorithm #Hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
pylori test (GI symptoms ... (CVID, WAS), (neurologic ... gastric bypass), LFT ... (liver disease) ... Causes #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... or higher • Liver ... diagnosis #workup #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... and symptoms can ... lymph node, or liver ... • Bicytopenia Treatment ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... mineralization Symptoms ... respiratory failure • Neurologic ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology
Portopulmonary Hypertension Presence of pulmonary arterial hypertension in a patient with portal hypertension No other obvious causes (chronic
m/s • Other signs ... pressure < 15mmHg TREATMENT ... through reduced cGMP metabolism ... hemodynamics Liver ... diagnosis #management #hepatology
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
neuropsychiatric symptoms ... • Caused by liver ... other causes of neurologic ... Initiate empiric treatment ... #hepatology
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