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diagnosis differential management pediatrics treatment algorithm nephrology 21hydroxylasedeficiency 21ohd acromegaly ammonia brue encephalopathy event genetics hyperammonemia lifethreatening neurology nutrition posterior
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm Cardiac: • Congenital Heart Disease •
Causes of Apparent ... Threatening Event (ALTE ... Myocarditis Metabolic ... • Reye's Syndrome ... #Peds #Pediatrics
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Heat stroke - Metabolic ... 5X ULN • AST/ALT ... AST declines > ALT ... Diagnosis #Management #causes
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
from hormonal and metabolic ... changes and may cause ... deficiency (thiamine) Late ... Paresthesias • Rhabdomyolysis ... Differential #Diagnosis #Pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
iniury, Compartment syndrome ... , Heat stroke, Metabolic ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... Management #Summary #causes
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Short Stature (Late ... • Turner Syndrome ... CHF) • Inborn Metabolism ... Diagnosis #Algorithm #endocrinology ... #causes #pediatrics
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
although hepatic causes ... and decreased metabolism ... rare): - Reye syndrome ... (Peds) - Primary ... deficiency #Ammonia #Pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework Rhabdomyolysis = Destruction of skeletal muscle with leakage of contents into circulation.
aldolase, AST/ALT ... Glycogenolysis, Lipid metabolism ... Neuroleptic malignant syndrome ... • Metabolic and ... Differential #Diagnosis #Causes
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... , vomiting • Late ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Drug toxicity, Metabolic ... the underlying cause ... Seizures: Treat with AEDs ... until cause identified
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... or refractory cases ... Diagnosis #Management #Endocrinology
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