5 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... pathways that lead ... #Pathophysiology ... Medication #Targets #Drug ... #Endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates JAK-STAT pathway ... - Giantism or acromegaly ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Significant Adverse Drug ... Definition of EuDKA • Metabolic ... level < 200 mg/dL Pathophysiology ... diagnosis #management #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... pachydermoperiostosis, drugs ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Pathogenesis of Select Causes of Constipation in Adults and in Elderly

 • Mechanical (ex. Bowel Obstruction,
bowel contents • Metabolic ... Narrowed anorectal angle ... unknown, many pathways ... colonic motility • Drugs ... #constipation #pathophysiology