23 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... presentation - Clinical ... Toxicology #Diagnosis #Management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... Maternal Support - Critical ... #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... fibers Spectrum of Clinical ... Hypothyroid #Myopathy #pathophysiology ... signs #symptoms #endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Definition of EuDKA • Metabolic ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
Woltman’s sign on Physical Exam

53-year-old man presented with fatigue and sensitivity to cold. A physical examination
relaxation of the ankle ... Woltmans #Signs #PhysicalExam ... Hypothyroidism #Ankle ... Reflexes #Delayed #Clinical ... Video #Neurology #Endocrinology
Woltman’s sign on Physical Exam - Delayed relaxation phase of the ankle jerk reflex, seen in
relaxation phase of the ankle ... Woltmans #sign #PhysicalExam ... #clinical #video ... hypothyroidism #endocrinology ... #ankle #reflex
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... #Endocrinology ... #Treatment #Pathophysiology
Woltman’s sign on Physical Exam

Delayed relaxation phase of a deep-tendon reflex, seen in hypothyroidism

#Woltmans #sign #PhysicalExam
Woltmans #sign #PhysicalExam ... #clinical #video ... hypothyroidism #endocrinology ... #ankle #reflex
Woltman’s sign on Physical Exam

Delayed relaxation phase of a deep-tendon reflex, seen in hypothyroidism

#Woltmans #sign #PhysicalExam
Woltmans #sign #PhysicalExam ... #clinical #video ... hypothyroidism #endocrinology ... #ankle #reflex
Woltman's Sign of Hypothyroidism on Physical Exam

Delayed relaxation phase noted after eliciting Achilles tendon reflex.

#Woltmans #Sign
Hypothyroidism #PhysicalExam ... #clinical #video ... #achilles #ankle ... #reflex #endocrinology