35 results
Vitamin D Metabolism

#VitaminD #Metabolism #Pathophysiology #Endocrinology #Pathways
Vitamin D Metabolism ... #VitaminD #Metabolism ... #Pathophysiology ... #Endocrinology
Vitamin D Metabolism Pathways

Dr. Jamie Willows @jamiekwillows

#VitaminD #Metabolism #Pathways #pathophysiology #endocrinology
Vitamin D Metabolism ... jamiekwillows #VitaminD ... #Metabolism #Pathways ... #pathophysiology ... #endocrinology
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
Vitamin D Metabolism ... Fat-soluble vitamin ... mendesthiagob #VitaminD ... #Metabolism #endocrinology ... #pathophysiology
Causes of Hypercalcemia due to increased Vitamin D levels
 • The BIG 3:
Causes of Hypercalcemia ... due to increased Vitamin ... Genetic: Williams syndrome ... jamiekwillows #Hypercalcemia ... differential #diagnosis #endocrinology
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... and Management ... Disease (CKD) - Metabolism ... - DiGeorge Syndrome ... #endocrinology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Other humoral syndromes ... Excess vitamin ... Differential #Diagnosis #Endocrinology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... Vitamin D metabolic ... • Milk-alkali syndrome ... #Hypercalcemia ... #Causes #endocrinology
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... calcium)-alkali syndrome ... • Vitamin D intoxication ... calcium #high #endocrinology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... High PTH • Vitamin ... Phenytoin, Nephrotic Syndrome ... • Hereditary Vitamin ... Algorithm #Phosphate #endocrinology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... constellation of metabolic ... intracellular ions and metabolic ... hyperphosphatemia, #hypocalcemia ... acutekidneyinjury #Pathophysiology