19 results
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
of Diabetic Ketoacidosis ... of carbohydrate metabolism ... state and fat metabolism ... #Diabetic #Ketoacidosis ... #Endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Definition of EuDKA • Metabolic ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary

Symptoms:
• Abdominal pain
• Nausea
• Polyuria
• Polydipsia
• Vomiting
• Weight loss
•
Diabetic Ketoacidosis ... Diagnosis and Management ... Abdominal pain • Nausea ... #Ketoacidosis # ... #Endocrinology
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary

Symptoms:
• Abdominal pain
• Nausea
• Polyuria
• Polydipsia
• Vomiting
• Weight loss
•
Diabetic Ketoacidosis ... Diagnosis and Management ... Abdominal pain • Nausea ... #Ketoacidosis # ... #Endocrinology
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
have new-onset diabetes ... ketoacidosis (EDKA ... significant anion gap metabolic ... production, the rate of metabolism ... Treatment with IV
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
bodies are a normal metabolic ... • Diabetic ketoacidosis ... (DKA) - caused ... differential #diagnosis #management ... #endocrinology
Diabetic Ketoacidosis 
Management Priorities
1. Fluids 
2. Insulin 
3. Potassium 
4. Acidosis 
5. Re-establish oral fluids,
Diabetic Ketoacidosis ... Management Priorities ... Identification and treatment ... an underlying cause ... Diabetes #Management
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... Due to neuronal metabolism ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology ... #diabetes
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
from hormonal and metabolic ... changes and may cause ... Poorly controlled diabetes ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
adenomas that require treatment ... For pituitary masses ... Hyperprolactinemia • Diabetes ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology