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diagnosis liver management signs abnormal aflp algorithm alkaline apml clinical diabetes diabeticketoacidosis differential differentiation dka enzymes fatty hematology hyophosphatasia hypothyroidism
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
Hypothyroid Myopathy ... hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... #signs #symptoms ... #endocrinology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... postpartum): • Initial symptoms ... Liver #Pregnancy #hepatology
Myoedema in Hypothyroidism on Physical Exam Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... varied clinical symptoms ... hormone in almost all ... #neurology #endocrinology ... #hypothyroid
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 Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
• Incr Glucose Metabolism ... - Metabolic ... PO4 -> decr RBC ATP ... #diagnosis #pathophysiology ... #symptoms #signs
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
in 1923 Low ALP ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... The presence of metabolic ... syndrome criteria ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Due to neuronal metabolism ... resolves due to ATP ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... Differentiation #Syndrome
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