74 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade and Anticoagulant ... AntiCoagulation #Cascade #Anticoagulants ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
and Novel Oral Anticoagulants ... - Pathophysiology ... or a new oral anticoagulant ... traditional oral anticoagulant ... #Pharmacology #Pathophysiology
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... clotting #INR #heparin ... dabigatran #Pradaxa #management ... #pharmacology #
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Clearance of Oral Anticoagulant ... Warfarin - 100% Hepatic ... Apixaban - 75% Hepatic ... #DOAC #NOAC #Metabolism ... #Pharmacology #
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... PCC (Kcentra) - Heparin ... anticoagulation #doac #noac #pharmacology ... #hematology #reversal
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct ... #Oral #AntiCoagulant
Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage

The table summarizes the recommendations for adult patients on
molecular weight heparins ... Unfractionated heparin ... Anticoagulation #Anticoagulants ... IntracranialHemorrhage #ICH #Management ... #Pharmacology #
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
direct-acting oral anticoagulants ... direct-acting oral anticoagulant ... molecular weight heparin ... Anticoagulation #Management ... #Hematology #Oncology
Heparin Induced Thrombocytopenia (HIT) - Likelihood, Diagnosis and Management
 - HIT Suspected
 - Calculate 4T Score
Heparin Induced ... - Likelihood, Diagnosis ... and Management ... Thrombocytopenia #Algorithm #Diagnosis ... #Management #Hematology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Mechanism of Action in Hepatic ... #Lactulose #pharmacology ... mechanism #ammonia #hepatology ... #pathophysiology