44 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade and Anticoagulant ... AntiCoagulation #Cascade #Anticoagulants ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct ... #Oral #AntiCoagulant
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... Diagnosis of MALA ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis ... #Management
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology
Pharmacology, Toxicity and Management of Second Generation Antipsychotic (SGA) Overdose #Diagnosis #Management #Toxicology #Psychiatry #SGA #SecondGenerationAntipsychotics
Pharmacology, Toxicity ... and Management ... SGA) Overdose #Diagnosis ... #Management #Toxicology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology ... #management #pathophysiology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... - Diagnosis and ... show anion-gap metabolic ... Labs: Anion-Gap Metabolic ... #Toxicology #diagnosis
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
Amiodarone Toxicity ... #Amiodarone #Toxicity ... SideEffects #Adverse #Diagnosis ... #Management #Pharmacology
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... deterioration Shock and metabolic ... - Anion gap metabolic ... #Toxicology #Diagnosis ... #Management #Ferrous
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Kfischer_10 #Anticoagulant ... anticoagulation #pharmacology ... #management #hematology