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Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... → Hypokalemia Metabolic ... #Syndrome #Pathophysiology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... constellation of metabolic ... intracellular ions and metabolic ... acutekidneyinjury #Pathophysiology ... Presentation #TLS #Workup
Hypoglycemia Workup and Differential Diagnosis
Workup:
 • Sulfonylurea Labs
 • Anti-lnsulin Ab - Insulin Autoimmune Syndrome
 •
Hypoglycemia Workup ... Insulin Autoimmune Syndrome ... tumor burden & metabolic ... Insulin Autoimmune Syndrome ... Diagnosis #insulinoma #endocrinology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Blood Work: - ... Hypomagnesemia - Metabolic ... dr_missyhanna #Gitelman ... #Syndrome #Diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... hypomagnesemia • Metabolic ... Hypochloremic metabolic ... nephrology #management #pathophysiology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... hypokalemia and metabolic ... Vasculitis • Endocrinologic ... White-coat syndrome ... #Hypertension #Workup
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... Diagnosis and Workup ... Diagnosis #Management #Endocrinology