11 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... obstruction • ALP ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... Shock liver • Metabolic ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... = nonspecific (nausea ... Liver #Pregnancy #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
significant portal HTN Signs ... and hepatorenal syndrome ... • Budd Chiari syndrome ... pregnancy • Primary biliary ... #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... The presence of metabolic ... syndrome criteria ... include extrahepatic biliary ... Abnormal #Algorithm #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... Nephrolithiasis • Metabolic ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... concentration (bowel or biliary ... Jcortesizaguirr #Ascites #workup ... Differential #Diagnosis #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... diagnosis #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Nephrotic Syndrome ... considered in all ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... involve one, two, or all ... Workup: • Complete ... #diagnosis #hematology