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Guillain-Barre Syndrome
An acute polyneuropathy (disorder Of the peripheral nervous System).
Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... An acute polyneuropathy ... GuillainBarre #Syndrome ... #Diagnosis #Neurology ... #Signs
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Syndrome Features ... Syndrome: • Progressive ... Miller Fisher syndrome-Bickerstaff ... hexacarbon abuse • Acute ... #Syndrome #diagnosis
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Polyneuropathy, Acute ... stroke, Acute spinal ... Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... diagnosis #table #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... - Summary Acute ... cardiomyopathy, Horner syndrome ... Miller Fisher Syndrome ... #Syndrome #diagnosis
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Hyperviscosity Syndrome ... Leukostasis: • WBC ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome ... Hyperuricemia • Acute
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... Fabry's disease, Acute ... differential #diagnosis #causes ... #neurology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... hematuria • Signs ... • Nutcracker syndrome ... #urology #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
suggestive of acute ... in a variety of acute ... suggestive of nephrotic sydnrome ... : • RBC Casts - ... Urine #Microscopy #nephrology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
renal bruit or signs ... Hypercalcemia, Cushing's syndrome ... White-coat syndrome ... , and Guillain-Barre ... Syndrome - Dr
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... syndrome • Triggers ... >100k, + lab signs ... rasburicase Tumor Lysis Syndrome ... #Tumor #Lysis #Syndrome