23 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... not required in all ... or if a primary hematologic ... #Workup #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Differential Diagnosis Algorithm ... Membrane Disorder ... Disorder - Acquired ... #Causes #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... evaluation or workup ... symptoms (eg, skin ... #diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Vasculitis - Collagen disorders ... , EGPA, Microscopic ... deficiency Work ... cryoglobulins • Skin ... #Causes #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... Polyarteritis nodosa • Microscopic ... #dermatology #rash ... #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... AML: Blast crises ... count ↑ PLT • ↑ PBS ... -> Invade Skin: ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Lymphocytosis on CBC ... lymphoproliferative disorders ... Leukemia #diagnosis #workup ... #oncology #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic Algorithm ... (MCV): Average RBC ... (BM) ablative disorders ... #Diagnosis #Workup ... #Hematology #Microcytic
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Consider sickle cell ... membrane disorder ... Differential #Diagnosis #Algorithm ... #workup #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... gammopathy, and skin ... autoimmune hepatitis, PBC ... gastric tumors • Hematology ... differential #diagnosis #hematology