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diagnosis hematology oncology algorithm causes acidosis bandemia cbc chronic cll disorders elevation erythematosus gap globulin hemolytic hodgkins lactate lactic leukemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Algorithm • Sickle cells ... Consider sickle cell ... Diagnosis #Algorithm #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Lymphocytosis on CBC ... Scoring system: ... • Neutropenia, anemia ... Leukemia #diagnosis #workup
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... precursors" • Stab cell ... count on initial evaluation ... #differential # ... #CBC #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... changes), high MCV anemia ... - Bone marrow evaluation ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... from ischemia WBC ... count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... platelets - WBC ... Immunohistochemical studies (to differentiate
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... +Organomegaly+↑RBC ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... frequently affected systems ... Better call hematology ... else is driving RBC ... you’ll do a good workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Angioimmunoblastic T-cell ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... of Circulatory System ... 30mmHg) - Severe anemia ... #typea #typeb #classification
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