8 results
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... considered first-line ... #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry
Nail diseases and disorders.
 - Spoon Nails (Koilonychia)
 - Pitting of Nails
 - Beau's Lines
 -
Nails - Beau's Lines ... white spots) #Diagnosis ... #Differential # ... #Leukonychia #Table ... #Clinical #PhysicalExam
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
without platelet ... MYH9-Related Disorder ... Defects #comparison #table ... #differential # ... diagnosis #hematology
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
lesion parallel to lines ... palms/soles - Differential ... diagnosis: secondary ... rosea #clinical #dermatology ... #photo #PhysicalExam
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... #Causes #dermatology ... #physicalexam
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
macule and papule (Table ... diagnosis; however ... diagnosis, which ... pathognomonic for SJS ... #Diagnosis #Dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... diverse genotypes): SS ... with or without platelet ... Consider RBC membrane disorder ... #workup #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Resolution > 15 days Differentials ... drug reaction • SJS ... Second Line Therapy ... DRESS #Syndrome #dermatology