6 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia ... #diagnosis #signs
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
... laboratory tests ... Alzheimer - 1st cause ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... - 2nd cause after
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Vestibulo-ocular ... • Examine for signs ... Casey Albin MD @ ... caseyalbin #PhysicalExam
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... Passive neck flexion causes ... an involuntary reflex ... Clinical #Video #PhysicalExam ... #Pediatrics #Peds
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Ocular- 50%: Ptosis ... Bedside: ice pack test ... /Edrophonium test ... - Cogan sign ... - Peek sign 2.
Newborn Infant - Routine Examination

Birthweight, gestational age and birthweight percentile are noted.
General observation Of the baby's
is also a late sign ... This reflex is not ... Newborn #Infant #PhysicalExam ... #Examination #Peds ... #Pediatrics #Diagnosis