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diagnosis hematology oncology dermatology differential downs erythematosus management manifestations mds monoclonal myelodysplasia myelodysplastic paraproteinemias sapho signs sle syndromes systemic
Characteristic clinical manifestations of Down syndrome Typical craniofacial appearance • Round face and flat
• Brushfield spots ... iris (pigmented spots ... neck • Single ... #PhysicalExam # ... Features #Signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Non-autoimmune rheumatologic ... Clinical Features ... • Malar rash - spares ... Erythematosus #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Entities That Can Feature ... • Heavy Chain disease ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
pain Clinical Features ... skeleton-sacroiliac joint and spine ... sites such as the collar ... osteoarticular and skin disease ... #Rheumatology #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... Myeloproliferative Disease ... with single-lineage ... characteristic feature ... #diagnosis #hematology
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