19 results
Causes of Primary and Secondary Amenorrhea - Differential Diagnosis Algorithm
Primary Amenorrhea - No onset of menarche
Causes of Primary ... • Central - Pituitary ... estrogen: • Pituitary ... Prolactin • Pituitary ... Diagnosis #Algorithm #Causes
Causes of Secondary Amenorrhea - Differential Diagnosis Algorithm
Absence of menses for more than 3 cycles or
Causes of Secondary ... Amenorrhea - Differential ... sarcoidosis) Pituitary ... #Secondary #Amenorrhea ... Diagnosis #Algorithm #Causes
Causes of Primary Amenorrhea - Differential Diagnosis Algorithm
No onset of menarche by age 16 with secondary
Causes of Primary ... Amenorrhea - Differential ... puberty Central - Pituitary ... Hypothyroidism #Primary #Amenorrhea ... Diagnosis #Algorithm #Causes
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... masses of all sizes ... Headaches • Nausea ... mnemonic #GLFTAP #pathophysiology
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Hypothalamus -> Pituitary ... • Amenorrhea ... , and/or limbs caused
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... - GH-secreting pituitary ... • Pituitary ... or refractory cases ... Endocrinology #Treatment #Pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
on the anterior pituitary ... and release LH causes ... #OvarianCycle #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... -> Particular CD4 ... Allergy #Immunology #pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... - Erosions and crusts ... not feasible CMC
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Drugs, Unknown cause ... 100 mg/m2) : in case ... emergency, ICU in case