2551 results
Algorithm for the outpatient management of thrombocytopenia. 
(DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
Algorithm for the ... outpatient management ... enzymes, and low platelet ... #Diagnosis #Management
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Splenomegaly Diagnosis ... A conclusive diagnosis ... • Treatment algorithms ... ET #hematology #diagnosis ... #management #hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... #differential #diagnosis
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Intracranial hemorrhage Management ... children) • Platelets ... extremely low platelet ... Thrombocytopenia #Diagnosis
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
based therapy and Management ... cryoprecipitate If platelets ... < 50 - > platelet ... Thromboelastography #TEG #Management ... #Diagnosis #Hematology
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
Thromboelastography (TEG) Based Management ... cryoprecipitate - If platelets ... < 50 -> platelet ... Thromboelastography #TEG #Management ... #treatment #diagnosis
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... #differential #diagnosis
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
- Differential Diagnosis ... Platelet Count ... #Differential #Diagnosis ... #causes #Platelets
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Suspected HIT Algorithm ... Thrombocytopenia (platelet ... Timing of onset of platelet ... HIT #hematology #diagnosis ... #4Ts #algorithm
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
- Differential Diagnosis ... Algorithm • Vascular ... vs Acquired • Platelet ... #Differential #Diagnosis ... #Algorithm #pathophysiology