9 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Inflammatory mechanism of asthma ... cytokines such as IL ... -5 and IL-1 3, which ... #asthma #pathophysiology
LABA/ICS Combination Inhalers
Long-Acting Beta2 Agonists (LABA) + Inhaled Corticosteroid (ICS) - Commonly used in Asthma 
Advair
Commonly used in Asthma ... (see one of my old ... that is dosed 1 ... Naming #Names #Pharmacology ... #Asthma
Dupixent (dupilumab) for Asthma
Dupixent (dupilumab) is a biologic medication that is a dual inhibitor of IL4
dupilumab) for Asthma ... dual inhibitor of IL4 ... dermatitis as well as asthma ... dose followed by 1 ... #Management #Pharmacology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... arthritic flare. 1. ... to Manifest: 1. ... Gout #Comparison #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... CNS • Headache, mild ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... • Interstitial Pneumonitis ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
Primatene Mist  - Epinephrine OTC Inhaler

Primatene Mist was approved in November and has been available
from before the old ... asthma symptoms ... prime it with 1 ... #OTC #Inhaler #Pharmacology ... #Asthma
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Disease (CPPD) Pathophysiology ... trauma (> 65 years old ... disease states 1. ... Deposition #Disease #Rheumatology