6 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
severity of the disease ... and ILD • Liver ... Phenotype 1 ... #rheumatology # ... dermatology #diagnosis
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... • Underlying disease ... states Pathophysiology ... to Manifest: 1. ... Gout #Comparison #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition Disease ... (CPPD) Pathophysiology ... trauma (> 65 years old ... states 1. ... #Rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, dermatomyositis ... Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
had more severe disease ... Prednisone at 1 ... methylprednisolone 1 ... diagnosis #management #rheumatology ... #dermatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
dysfunction. 1. ... ▪ Autoimmune diseases ... Pathophysiology ... ., IFN-γ, TNF, IL ... Diagnosis #Management #Hematology