49 results
Pulmonary complications of targeted therapy
-Immune checkpoint inhibitors (e.g. pembrolizumab)
-Pneumonitis is uncommon (~5% of patients) but can
exclusion: rule out infection ... during therapy. -1/ ... associated with a clinical ... #Clinical #Diagnosis ... #Radiology #Honc
Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic
Nodular pattern 1. ... Hypersensitivity pneumonitis ... : ill defined centrilobular ... Hypersensitivity pneumonitis ... #Clinical #Radiology
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
nodular pattern. 1. ... Hypersensitivity pneumonitis ... Hypersensitivity pneumonitis ... #Clinical #Diagnosis ... #Radiology #Pulmonary
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
Mild infection: ... Mild infection: ... erysipelas with no focus ... oral antibiotic treatment ... or those with clinical
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... accumulation of clinical ... Assessment • Clinical ... Unknown cause Treatment ... #summary #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
AM stiffness, >1 ... Ultrasound Diagnosis: CLINICAL ... exam and imaging Treatment ... corticosteroid injections ... diagnosis #management #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... Manifestations: 1) ... Infection due to ... Agents: 1) ... Leukemia #oncology #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... Fever is the main clinical ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... • Clinical Manifestations ... life-threatening • Treatment ... comparison #table #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
within the first 1 ... decrease in HIV-1 ... noncompliance • Clinical ... initiation Clinical ... ocular • PJP - Pneumonitis