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diagnosis syndrome antinxp2 antinxp2dm calcium cppd deposition dermatology dermatomyositis disease erythematosus lupus macrophage mas pseudogout pyrophosphate sjogrens sle systemic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... -1 and IL-6, leading ... rash) • Heart, lung ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1, ... Chronic B-cell activation ... Erythematosus #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
• Interstitial Pneumonitis ... phenomenon (16%) MSK ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Non-small-cell lung ... Dermatomyositis: • ILD ... Prednisone at 1 ... Dermatomyositis #diagnosis #management ... #rheumatology #
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
trauma (> 65 years old ... disease states 1. ... ≥2 attacks • Long-term ... Deposition #Disease #Rheumatology ... #diagnosis #management
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