9 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... -1 and IL-6, leading ... rash) • Heart, lung ... #Diagnosis #Management ... #Hematology #Rheumatology
Monteggia Fracture 
Fracture of proximal ulnar shaft with radial head dislocation. Remember “MUGR” to recall where
), compartment syndrome ... Splint: Posterior long ... if types I or Ill ... followup within 1 ... Orthopedics #Proximal #MSK
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... • Chronic lung ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... -1 inhibitors, IL ... #Rheumatology # ... diagnosis #management ... #Dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... CNS • Headache, mild ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced Lung ... respiratory distress syndrome ... including: 1. ... Exclusion of other ILDs ... Pulmonary #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
• Interstitial Pneumonitis ... phenomenon (16%) MSK ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Dermatomyositis: • ILD ... Prednisone at 1 ... Dermatomyositis #diagnosis #management ... #rheumatology # ... dermatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
trauma (> 65 years old ... disease states 1. ... Crowned Dens Syndrome ... Deposition #Disease #Rheumatology ... #diagnosis #management