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Diagnostic algorithm for idiopathic pulmonary fibrosis, in part adapted from the ATS/ERS consensus statement. HRCT =
idiopathic pulmonary fibrosis ... HRCT = high-resolution ... computerised tomography; ILD ... = interstitial lung ... usual interstitial pneumonitis
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Hypersensitivity pneumonitis ... • Radiation pneumonitis ... Idiopathic Interstitial Pneumonias ... Idiopathic pulmonary fibrosis ... #diagnosis #differential
Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic
Nodular pattern ... Hypersensitivity pneumonitis ... : ill defined centrilobular ... Clinical #Radiology #HRCT ... #Comparison #Table
Figure 3 HRCT-LUS correlation in normal lung, pulmonary congestion, rheumatoid lung disease, idiopathic pulmonary fibrosis.
Notes: (A)
Figure 3 HRCT-LUS ... idiopathic pulmonary fibrosis ... artifact); (G) UIP pattern ... Clinical #Diagnosis #HRCT ... #Table #ILD #Findings
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
Upper lung zone ... bronchiolitis (RB-ILD ... Hypersensitivity pneumonitis ... #ChestCT #Differential ... #Table #Distribution
High Attenuation pattern (2) 
1. Non specific interstitial pneumonitis (NSIP): ground glass with traction bronchiectasis, no
High Attenuation pattern ... specific interstitial pneumonitis ... result of massive fibrosis ... Clinical #Radiology #HRCT ... #Comparison #Table
Chronic hypersensitivity pneumonitis
The key findings in chronic hypersensitivity pneumonitis are:
Mosaic pattern with areas of ground-glass atenuation
are: Mosaic pattern ... Fibrosis and parenchymal ... The HRCT shows a ... mosaic pattern ... existing irreversible fibrosis
Approach to the diagnosis of chronic hypersensitivity pneumonitis. 
*Consider additional test: bronchoscopy with bronchoalveolar lavage, transbronchial
hypersensitivity pneumonitis ... hypersensitivity pneumonitis ... ; HRCT = high-resolution ... hypersensitivity #pneumonitis ... algorithm #HP #ILD
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... in interstitial lung ... low attenuation (table ... is interstitial lung ... #Differential #
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. 
They represent fundamental responses of
idiopathic interstitial pneumonias ... combinations of fibrosis ... listed in the table ... morphologic findings on HRCT ... IdiopathicInterstitialPneumonia #ILD