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diagnosis rheumatology druginduced lupus treatment comparison cop cryptogenic dil hemophagocytic hlh lymphohistiocytosis organizing pneumonia pulmonary sle summary table
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
pneumonia • formerly BOOP ... Unknown • 6-7 cases ... Pneumonia #COP #BOOP ... #pulmonary #ILD ... #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Prognosis: Usually mild ... Discontinuation of causal ... • Immunologic Workup ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... Auto-amplification loop ... Drugs, Unknown cause ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
• Immunologic Workup ... Prognosis: Usually mild ... Discontinuation of causal ... cutaneous-DIL • Evolution ... diagnosis #treatment #management
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