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diagnosis rheumatology lupus treatment ckd comparison druginduced erythematosus hemodialysis hemophagocytic hlh lymphohistiocytosis nephrology pruritus summary systemic table uremia uremic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... Usual therapeutic management ... of SLE • Evolution ... : Chronic disease ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... • Acute lupus pneumonitis ... CNS • Headache, mild ... vein thrombosis Hematologic
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... : SLE+++, Adult-onset ... Still disease, ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management
Management of Pruritus in Patients with Chronic Kidney Disease Pruritus with no primary lesions - differential diagnosis:
Management of Pruritus ... primary lesions - differential ... pruritus • Hematologic ... Use mild detergent ... Pruritus #Treatment #Algorithm
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