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hepatology liver obstetrics pregnancy aspergillus betadglucan biomarkers disease erythematosus fatty fungal galactomannan hellp hepatitis icp lupus obgyn pathophysiology rheumatology sle
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
of Pregnancy (AFLP ... obstetrics #hepatitis #comparison ... #differential # ... diagnosis #icp # ... HELLP #AFLP
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ↓Antithrombin Ill ... infiltration) Differential ... Diagnosis: Viral ... iMedEducation #AFLP
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) in hematologic ... useful in high risk ... BAL GM does not differentiate ... Galactomannan #diagnosis ... #comparison
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Malignancy (e.g. hematologic ... • Acute lupus pneumonitis ... Thrombosis highest risk
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