10 results
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... DWI+ in acute disease ... #Syndrome #Clinical ... #MRI #Brain #Diagnosis ... #Radiology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
- Differential Diagnosis ... Oral sodium loading ... CT or MRI scan of ... • Cushing’s syndrome ... #Differential #Diagnosis
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Chorioretinitis • Diagnosis ... - Compatible syndrome ... + MRI lesions + ... RingEnhancing #Lesions #Brain ... #causes #radiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
parietal lobes of the brain ... Shock, Autoimmune disease ... factor PRES Diagnosis ... Vascular narrowing on MRA ... parietal lobes of the brain
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... IL-1 and IL-6, leading ... Liver function tests ... Histopathologic criteria ... #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... Criteria: • Sensory ... negative, MOG-IgG test ... ruled out • Brain ... brain and/or optic
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... 10 minutes of rest ... Criteria: • Underlying ... 80mmHg or A-a gradient ... hepatopulmonary #syndrome
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
Alteration in brain ... over course of disease ... Malnutrition, TIPS West ... Haven Criteria: ... Encephalopathy #Grading
Palpitations - Differential Diagnosis Framework

What?
• It is an unpleasant awareness or sensation that the heart is
- Differential Diagnosis ... heart is pounding, racing ... Palpitations Diagnosis ... due to decreased brain ... #Palpitations #Cardiology
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
including anterior or posterior ... and nephrotic syndrome ... but do not meet criteria ... Latent #Tertiary #Diagnosis ... of Infectious Diseases