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diagnosis syndrome rheumatology als amyotrophic arteritis arthritis clinical differentiation encephalopathy gca giantcell gout gouty gravis lateral leukostasis lysis myasthenia myelitis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... endothelial damage Prophylaxis ... initiation • Differential ... #diagnosis #management ... #hematology #oncology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... mass and NO prior signs ... - **MSK rads ... Differential diagnosis ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... leukapheresis - TLS prophylaxis ... TLS #diagnosis #management ... #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... cord compression (MRI ... • Bilateral signs ... Myelitis #diagnosis #management ... #neurology #differential
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... MRI: Brain, cervical ... conditions listed in differential ... Lateral #Sclerosis #neurology ... #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Reversible course Differential ... Syndrome #diagnosis #management ... #neurology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... very remarkable w/differential ... GCA #Temporal #Signs ... Symptoms #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... affects the skin, neurologic ... oligoclonal bands • MRI ... tract, and often causes
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