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differential causes oncology rash generalized leukemia pruritus secondary systemic anemia aplastic chronic cll ddxof erythematous febrile immunecompromised immunocompromised lymphocytic maculopapular
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... instability - New-onset fever ... sulfa-drug - Skin ... #Dermatology #Rash ... Maculopapular #Scaling #Color
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... redness of the skin ... staphylococcal scalded skin ... #Diagnosis #Dermatology ... Erythematous #Rash #Algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... Algorithm - Systemic ... Myelodisplastic syndrome Psychiatric ... #generalized #dermatology ... #Algorithm #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... color • Difficulty ... breathing • Neutropenia ... Anemia #oncology #hematology ... #diagnosis #management
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... Red Flags: • Fever ... cryoglobulins • Skin ... #dermatology #physicalexam
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... - Differential Diagnosis ... Algorithm Structural ... CNS Infection Neutropenia ... #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... - Differential Diagnosis ... Algorithm Blood ... Myelodisplastic syndrome Psychiatric ... #generalized #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... Cytopenias: • Neutropenia ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... or functional neutropenia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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