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hematology coagulation differential abnormal causes prolonged anticoagulant anticoagulation bleeding bruising cascade clot dabigatran edoxaban hemostasis heparin inhibitor models pathophysiology pathway
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... Congenital intrinsic ... drugs e.g. direct thrombin ... intravascular coagulation (DIC ... #Causes #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... PT and the aPTT ... affected in the intrinsic ... drugs (e.g. direct thrombin ... intravascularcoagulation (DIC
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
along with FXIIa (intrinsic ... Thrombin, then primes ... #clot #PT #PTT ... #diagnosis #models ... #inhibitor #Apixaban
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... Warfarin • Acute DIC ... pathway to the intrinsic ... disease • Acute DIC ... warfarin, direct thrombin
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