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rheumatology autoimmune classification dermatology dress erythematosus hlh immune iris lupus lymphohistiocytosis macrophage myopathy myositis oncology polychondritis reconstitution relapsing sle summary
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... number of sites of disease ... Lymphoma Treatment ... #lymphoma #diagnosis ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... production of pro-inflammatory ... • Clinical: fever ... Hemopathies+++: Hodgkin ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... A subset of hemophagocytic ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... weight loss, and fever ... permanent alopecia Differential ... Chronic B-cell activation ... cyclophosphamide) • Hodgkin
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Fever >38.5 2. ... Resolution > 15 days Differentials ... : symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Syndrome - Overview ... worsening of that disease ... Leishmaniasis Differential ... #Syndrome #Differential ... #Diagnosis #Management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Nonspecific symptoms: Fever ... Inflammatory ... Viral infection • Lymphoma ... affected tissue Treatment ... #diagnosis #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Inflammatory ... : Fever, joint pain ... statins - probably caused ... #differential #
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