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rheumatology classification erythematosus hlh lymphohistiocytosis macrophage oncology polychondritis relapsing sle summary systemic
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... number of sites of disease ... Lymphoma Treatment ... #lymphoma #diagnosis ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
production of pro-inflammatory ... • Clinical: fever ... Hemopathies+++: Hodgkin ... Drugs, Unknown cause ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Syndrome (MAS) ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... weight loss, and fever ... permanent alopecia Differential ... Chronic B-cell activation ... cyclophosphamide) • Hodgkin
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... Nonspecific symptoms: Fever ... Viral infection • Lymphoma ... affected tissue Treatment ... #diagnosis #management
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