10 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
production of pro-inflammatory ... • Clinical: fever ... Hemopathies+++: Hodgkin ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... A subset of hemophagocytic ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... number of sites of disease ... Lymphoma Treatment ... classification #hematology ... #oncology #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Fever >38.5 2. ... Resolution > 15 days Differentials ... : symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rule out other causes ... and lower jaw Treatment ... osteoarticular and skin disease ... diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... weight loss, and fever ... permanent alopecia Differential ... Chronic B-cell activation ... cyclophosphamide) • Hodgkin
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
- OnePager Summary ... hematuria) • Inflammatory ... Goodpasture's cause ... diagnosis #management ... #treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Syndrome - Overview ... worsening of that disease ... Leishmaniasis Differential ... #Syndrome #Differential ... #Diagnosis #Management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... acute neck pain, fever ... diagnosis #management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Nonspecific symptoms: Fever ... chondritis • Inflammatory ... Inflammatory ... affected tissue Treatment ... #diagnosis #management