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hlh lymphohistiocytosis rheumatology aids classification cns dermatology dress endocarditis hiv hodgkins infections inflammatory lymphoma macrophage neurology oncology opportunistic reconstitution summary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... that disrupts immune ... • Clinical: fever ... Drugs, Unknown cause ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... A subset of hemophagocytic ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... underlying genetic immune ... following: • Fever ... #management #treatment ... #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... worsening of that disease ... #IRIS #Immune ... #Differential # ... Diagnosis #Management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Fever >38.5 2. ... Resolution > 15 days Differentials ... : symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Antimicrobial treatment ... required until immune ... Demyelinating disease ... caused by the JC ... opportunistic #InfectiousDiseases
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Erythema nodosum • Immune ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #oncology #management
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
- Overview and Differential ... Cholesterol emboli syndrome ... hematuria, + RF Treatment ... #Diagnosis #cardiology ... #infectiousdiseases
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