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diagnosis differential endocrinology causes algorithm clinical management hyperthyroidism pathophysiology hypothyroidism neck otolaryngology radiology ophthalmology signs anatomy goiter physicalexam symptoms mass
Thyroid Disorders - Differential Diagnosis Algorithm Hypothyroidism: • Hasimoto’s • Radioactive Iodine • Hypopituitarism • Iodine
Thyroid Disorders ... Hasimoto’s • Radioactive ... @AmyChung #Thyroid
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
of Patients for Thyroid ... normal or increased radioactive ... normal or increased radioactive ... increased; decreased radioactive ... normal; decreased radioactive
Differentiation of Causes of Hyperthyroidism According to Pattern of Radionucleotide Uptake Reduced uptake: • Thyroiditis • Exogenous
loading • Ectopic thyroid ... disease • Excess thyroid-stimulating ... adenoma #rai #radioactive
Graves' Disease Treatment Thionamides (mainly methimazole) • Chance of remission in up to 2 years • No
2 years • No thyroid ... 40%) • Low cost Radioactive
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
with circulating thyroid ... ↑ Free T4 • Thyroid ... suspected • Thyroid ... scintigraphy with radioactive ... Methimazole and PTU) • Radioactive
Approach to the Diagnosis of Hyperthyroidism - Differential Diagnosis and Workup Algorithm • Secondary Hyperthyroidism (↑↔TSH,
T3/Free T4) Radioactive ... Multinodular goiter Radioactive ... • Exogenous thyroid
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
Diagnostic Algorithm Radioactive ... concern for nodular thyroid
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... symmetrically enlarged thyroid ... with TRAb → Radioactive
Radiation Injury Acute Radiation Toxicity primarily affects rapidly dividing cells based on dosage Hematopoiteic - Pancytopenia, Infection •
If exposed to radioactive ... iodide to prevent thyroid
Figure 2. The “laryngeal handshake,” from left to right: 1) hyoid, 2) thyroid, 3) cricoid, and
left to right: 1) hyoid ... , 2) thyroid, 3)
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