8 results
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
dL the ULN R - Renal ... Look for gamma gap ... Causes of false- ... macroglobulinemia, and autoimmune ... Gammopathies #MGUS #diagnosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
OnePager Summary Autoimmune ... vasculitis (AAV): GPA ... antibody, Anti-GBM ... Goodpasture's cause ... hematuria, RBC casts
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
acute HIV, HBV, EBV ... Cirrhosis, ETOH, autoimmune ... cancers, HCC, renal ... #differential #diagnosis ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... mucositis - Rash ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... , mucositis • Rash ... MPO > PR3 60/ GPA ... tract, and often causes ... #Rheumatology
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
confirming the diagnosis ... Although the cause ... thought to be an autoimmune ... #NEJM #clinical ... lichen #planus #derm
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... Symptoms: • Gottron rash ... • ANA < 20 % IBM ... statins - probably caused ... Myositis #Myopathy #rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
cartilage in the body (Autoimmune ... • Lymphoma • GPA ... /EGPA • RA Diagnosis ... Polychondritis #rheumatology ... #diagnosis #management